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Separate predictors from digoxin include in customers which have (kept panel) and you will instead atrial fibrillation (proper panel)

Standard features out of clients having heart incapacity with reduced ejection tiny fraction with and you may as opposed to reputation for atrial fibrillation stratified because of the digoxin explore throughout the overall inhabitants

AF, atrial fibrillation; ASA, acetylsalicylic acid; Body mass index, bmi; CAD, coronary artery situation; COPD, persistent obstructive pulmonary state; DBP, diastolic hypertension; ECG, electrocardiogram; EF, ejection small fraction; FU, follow-up; GFR, glomerular filter rate; HF, center inability; Hours, heartrate; ICD/CRT, intracardiac defibrillator/cardiac resynchronization medication; IHD, ischaemic heart problems; MBP, mean blood pressure; MRA, mineralocorticoid receptor antagonists; NT-proBNP, N-terminal expert-brain natriuretic peptide; NYHA, Nyc Cardio Connection; RASi, renin–angiotensin program inhibitor (angiotensin-transforming chemical substance, angiotensin receptor blocker, otherwise angiotensin receptor/neprilysin substance); Mat, peripheral artery state; SBP, systolic blood circulation pressure; and you may SMD, standard imply difference.

b As part of the numerous imputation model (although not fundamentally imputed if there are not any missing data) and you can logistic/Cox activities.

a propensity scores (PSs) having digoxin fool around with was in fact by themselves calculated when you look at the per imputed analysis set from the an excellent logistic regression design plus the variables showcased into the Dining table 1 while the covariates, and then averaged along side 10 imputed study establishes, getting people having and you will instead of AF. Modified Cox regression patterns was indeed did partly on PS-coordinated cohort and partly on complete cohort like the PS while the an excellent covariate.